Электронная книга: Hugo Kubinyi «Drug Metabolism Prediction»

Drug Metabolism Prediction

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying principles. They aim to convey their expert knowledge distilled from many years of experience in the field. In addition to the fundamentals, computational approaches and their applications, this volume provides expert accounts of the latest experimental methods for investigating drug metabolism in four dedicated chapters. The authors discuss the most important caveats and common errors to consider when working with experimental data. Collating the knowledge gained over the past decade, this practice-oriented guide presents methods not only used in drug development, but also in the development and toxicological assessment of cosmetics, functional foods, agrochemicals, and additives for consumer goods, making it an invaluable reference in a variety of disciplines.

Издательство: "John Wiley&Sons Limited"

ISBN: 9783527672998

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См. также в других словарях:

  • Drug metabolism — is the biochemical modification of pharmaceutical substances by living organisms, usually through specialized enzymatic systems. This is a form of xenobiotic metabolism. Drug metabolism often converts lipophilic chemical compounds into more… …   Wikipedia

  • Drug design — Not to be confused with Designer drug. Drug design, also sometimes referred to as rational drug design or structure based drug design, is the inventive process of finding new medications based on the knowledge of the biological target.[1] The… …   Wikipedia

  • Drug discovery — In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered and/or designed. In the past most drugs have been discovered either by identifying the active ingredient from traditional… …   Wikipedia

  • Simcyp — is a University of Sheffield spin out company that develop algorithms along with population and drug databases for modelling and simulation (M S) of the absorption and disposition of drugs in patients and specific subgroups of patients across… …   Wikipedia

  • CYP3A4 — Cytochrome P450, family 3, subfamily A, polypeptide 4 Structure of CYP3A4 (from PDB 1W0E). Heme group visible at center …   Wikipedia

  • Cyprotex — Discovery Ltd Type Public Industry Pharmaceutical Biotechnology Founded 1999 Headquarters Macclesfield, UK Products Cloe SCREEN Cloe PK Cloe HIA …   Wikipedia

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