Электронная книга: Hugo Kubinyi «Combinatorial Chemistry. A Practical Approach»
|
As we enter the new millennium, combinatorial chemistry is providing significant impetus to new innovations in synthetic chemistry. Combinatorial chemistry has rapidly become the rising star among research methods, allowing scientists to efficiently test the feasibility of a multitude of new compounds. The pursuit of new drugs is but one challenging field in which these combinatorial methods are particularly advantageous, helping researchers meet the modern-day demands of a highly competitive environment. This book emphasises that modern combinatorial synthesis is possible not only in the solid phase, but also in solutions. Moreover, it discusses computer-assisted methods as well as the apparatus and instrumentation required for the combinatorial method. Successful and experienced researchers in the leading pharmaceutical companies and most renowned research institutes offer a solid insight and perspective into this diverse field. A'must'for every scientist in the area of pharmaceutical research Издательство: "John Wiley&Sons Limited"
ISBN: 9783527614158 электронная книга Купить за 16215.48 руб и скачать на Litres |
Другие книги автора:
| Книга | Описание | Год | Цена | Тип книги |
|---|---|---|---|---|
| Drug-Membrane Interactions. Analysis, Drug Distribution, Modeling | Barrier, reservoir, target site– those are but some of the possible functions of biological lipid membranes in the complex interplay of drugs with the organism. A detailed knowledge of lipid… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Drug Bioavailability. Estimation of Solubility, Permeability, Absorption and Bioavailability | The gold standard for industrial research now completely revised in line with current trends in the field, with all contributions extensively updated or rewritten. In 21 chapters readers can benefit… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Virtual Screening. Principles, Challenges, and Practical Guidelines | Drug discovery is all about finding small molecules that interact in a desired way with larger molecules, namely proteins and other macromolecules in the human body. If the three-dimensional… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Molecular Descriptors for Chemoinformatics. Volume I: Alphabetical Listing / Volume II: Appendices, References | The number-one reference on the topic now contains a wealth of new data: The entire relevant literature over the past six years has been painstakingly surveyed, resulting in hundreds of new… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Prodrugs and Targeted Delivery. Towards Better ADME Properties | This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Aspartic Acid Proteases as Therapeutic Targets | In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Chemokine Receptors as Drug Targets | Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine research, the pharmaceutical industry has… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Pharmacokinetics and Metabolism in Drug Design | In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Microwaves in Organic and Medicinal Chemistry | Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed, almost doubling the amount of chemical information with… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Protein-Protein Interactions in Drug Discovery | Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Bioisosteres in Medicinal Chemistry | Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Phosphodiesterases and Their Inhibitors | Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Antiviral Drug Strategies | By focusing on general molecular mechanisms of antiviral drugs rather than therapies for individual viruses, this ready reference provides the critical knowledge needed to develop entirely novel… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Protein-Ligand Interactions | Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга | ||
| Reactive Drug Metabolites | Closing a gap in the scientifi c literature, this first comprehensive introduction to the topic is based on current best practice in one of the largest pharmaceutical companies worldwide. The first… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга |
См. также в других словарях:
chemistry — /kem euh stree/, n., pl. chemistries. 1. the science that deals with the composition and properties of substances and various elementary forms of matter. Cf. element (def. 2). 2. chemical properties, reactions, phenomena, etc.: the chemistry of… … Universalium
List of important publications in chemistry — FoundationsThe Sceptical Chymist* Robert Boyle 1661Description: Boyle, in the form of a dialogue, argued that chemical theories should be firmly grounded in experiment before their acceptance, and for the foundation of Chemistry as a science… … Wikipedia
Force field (chemistry) — In the context of molecular mechanics, a force field (also called a forcefield) refers to the functional form and parameter sets used to describe the potential energy of a system of particles (typically but not necessarily atoms). Force field… … Wikipedia
DNA-encoded chemical library — DNA encoded chemical libraries (DEL) are a new technology for the synthesis and screening of collections of chemical compounds of unprecedented size and quality. DEL represents an advance in medicinal chemistry which bridges the fields of… … Wikipedia
Chemical biology — is a scientific discipline spanning the fields of chemistry and biology that involves the application of chemical techniques and tools, often compounds produced through synthetic chemistry, to the study and manipulation of biological systems.… … Wikipedia
Travelling salesman problem — The travelling salesman problem (TSP) is an NP hard problem in combinatorial optimization studied in operations research and theoretical computer science. Given a list of cities and their pairwise distances, the task is to find a shortest… … Wikipedia
