Электронная книга: Gisbert Schneider «De novo Molecular Design»

De novo Molecular Design

Systematically examining current methods and strategies, this ready reference covers a wide range of molecular structures, from organic-chemical drugs to peptides, Proteins and nucleic acids, in line with emerging new drug classes derived from biomacromolecules. A leader in the field and one of the pioneers of this young discipline has assembled here the most prominent experts from across the world to provide first-hand knowledge. While most of their methods and examples come from the area of pharmaceutical discovery and development, the approaches are equally applicable for chemical probes and diagnostics, pesticides, and any other molecule designed to interact with a biological system. Numerous images and screenshots illustrate the many examples and method descriptions. With its broad and balanced coverage, this will be the firststop resource not only for medicinal chemists, biochemists and biotechnologists, but equally for bioinformaticians and molecular designers for many years to come. From the content: * Reaction-driven de novo design * Adaptive methods in molecular design * Design of ligands against multitarget profiles * Free energy methods in ligand design * Fragment-based de novo design * Automated design of focused and target family-oriented compound libraries * Molecular de novo design by nature-inspired computing * 3D QSAR approaches to de novo drug design * Bioisosteres in de novo design * De novo design of peptides, proteins and nucleic acid structures, including RNA aptamers and many more.

Издательство: "John Wiley&Sons Limited"

ISBN: 9783527677009

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Gisbert Schneider

Gisbert Schneider (* 1934 in Wattenscheid) ist ein emeritierter Professor für künstlerisches Orgelspiel und Improvisation an der Folkwang Hochschule Essen und Kirchenmusikdirektor.

Geboren in Wattenscheid, wuchs er in Weimar auf. Dort erhielt er ersten Orgelunterricht bei Johannes Ernst Köhler. Das Kirchenmusik- und Kapellmeisterstudium absolvierte er bei Siegfried Reda an der Folkwang Hochschule Essen. Daran schloss sich eine Kirchenmusikertätigkeit in Velbert und Mülheim an der Ruhr an. Seit 1963 war er zudem Dozent an der Folkwang Hochschule Essen, 1970 wurde er zum Professor berufen.[1]

Er ist Preisträger internationaler Orgelwettbewerbe und erhielt 1958 den Förderpreis des Landes Nordrhein-Westfalen. Neben der internationalen Konzerttätigkeit war er Jurymitglied internationaler Orgelwettbewerbe. Besonders enge wissenschaftliche Kooperationen gab es mit der Musikakademie Krakau bzw. Jan Jargon. Von Gisbert Schneider gibt es Rundfunk und Schallplattenaufnahmen sowie CD/SACD-Einspielungen. Er war Gründer und mehr als 50 Jahre Leiter der Kantorei Velbert. 1996 wurde ihm das Bundesverdienstkreuz verliehen.[2]

Diskographie (unvollständig)

  • Wilhelm Middelschulte (1863-1943): Orgelwerke, Gisbert Schneider an der Großen Alexander-Schuke-Orgel im Dom zu Erfurt, Audio-CD 1997, Cybele Records
  • Johann Sebastian Bach: Orgelwerke auf der großen Silbermann-Orgel im Dom zu Freiberg, Gisbert Schneider, Mehrkanal SACD abspielbar auch auf herkömmlichen CD-Playern, 2003, Cybele Records



  1. www.uni-protokolle.de, abgerufen am 17. März 2010
  2. CD-Booklet J. S. Orgelwerke, Cybele

Источник: Gisbert Schneider

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