Электронная книга: Cheng Kun «Advanced Delivery and Therapeutic Applications of RNAi»

Advanced Delivery and Therapeutic Applications of RNAi

RNA interference (RNAi) is a process in living cells whereby small double stranded RNA interferes with the expression of specific genes with complementary nucleotide sequence. Like many nucleic acid-based therapies, RNAi has great potential in treating various life-threatening diseases. However, the poor stability and cellular uptake of RNAi molecules remain considerable barriers to their efficient delivery which is paramount to a successful therapy. This book provides a comprehensive introduction to RNAi delivery, then goes on to discuss different delivery strategies, and concludes with current applications in various diseases. It covers: Mechanisms, Barriers, and Analysis of RNAi Delivery Nonclinical Safety Assessments and Clinical Pharmacokinetics: A Regulatory Perspective Bioconjugation of siRNA for Site Specifi c Delivery Nanoscale Delivery Systems for RNAi Environmentally-Responsive Delivery Systems for RNAi Light-sensitive RNAi Viral-Mediated Delivery of shRNA and miRNA RNAi applications in Cancer Therapy, Liver Diseases, Hepatitis B, and Ocular Disease miRNA as therapeutic agents and targets Advanced Delivery and Therapeutic Applications of RNAi combines the essential aspects of developing RNAi therapeutics from bench to clinic, and is invaluable for researchers working on RNAi, drug discovery and delivery, biomedical engineering, biomaterials, molecular biology, and biotechnology.

Издательство: "John Wiley&Sons Limited"

ISBN: 9781118610756

электронная книга

Купить за 16151.91 руб и скачать на Litres

Cheng Kun

Cheng Kun may refer to the following people:

  • Cheng Kun (成昆), a fictional character in the novel The Heaven Sword and Dragon Saber
  • Cheng Kun (成坤), a fictional character in the novel Baifa Monü Zhuan

Источник: Cheng Kun

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Cheng KunAdvanced Delivery and Therapeutic Applications of RNAiRNA interference (RNAi) is a process in living cells whereby small double stranded RNA interferes with the expression of specific genes with complementary nucleotide sequence. Like many nucleic… — @John Wiley&Sons Limited, @ @ @ @ Подробнее...
16151.91электронная книга

См. также в других словарях:

  • RNA interference — (RNAi) is a mechanism that inhibits gene expression at the stage of translation or by hindering the transcription of specific genes. RNAi targets include RNA from viruses and transposons (significant for some forms of innate immune response), and …   Wikipedia

  • SiRNA — Saltar a navegación, búsqueda Artículo principal: RNAi El nombre siRNA son las siglas en inglés de small interfering RNA, en español ARN pequeño de interferencia o ARN de silenciamiento. Es un tipo de ARN interferente con una longitud de 20 a 25… …   Wikipedia Español

  • siRNA — Artículo principal: RNAi El nombre siRNA son las siglas en inglés de small interfering RNA, en español ARN pequeño de interferencia o ARN de silenciamiento. Es un tipo de ARN interferente con una longitud de 20 a 25 nucleótidos que es altamente… …   Wikipedia Español

  • РНК-интерференция — Доставка малых РНК, содержащих шпильки, при помощи вектора на основе лентивируса и механизм РНК интерференции в клетках млекопитающих РНК интерференция (а …   Википедия

  • Life Sciences — ▪ 2009 Introduction Zoology       In 2008 several zoological studies provided new insights into how species life history traits (such as the timing of reproduction or the length of life of adult individuals) are derived in part as responses to… …   Universalium


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