Электронная книга: Gerd Folkers «Protein Therapeutics»

Protein Therapeutics

In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades. Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.

Издательство: "John Wiley&Sons Limited"

ISBN: 9783527699131

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См. также в других словарях:

  • therapeutics — /ther euh pyooh tiks/, n. (used with a sing. v.) the branch of medicine concerned with the remedial treatment of disease. [1665 75; see THERAPEUTIC, ICS] * * * Treatment and care to combat disease or alleviate pain or injury. Its tools include… …   Universalium

  • Glucokinase regulatory protein — protein Name = caption = width = HGNCid = 4196 Symbol = GCKR AltSymbols = EntrezGene = 2646 OMIM = 600842 RefSeq = NM 001486 UniProt = Q14397 PDB = ECnumber = Chromosome = 2 Arm = p Band = 23 LocusSupplementaryData = The glucokinase regulatory… …   Wikipedia

  • Ca2+/calmodulin-dependent protein kinase — Calcium/calmodulin dependent protein kinase II association domain crystal structure of calcium/calmodulin dependent protein kinase Identifiers Symbol CaMKII AD …   Wikipedia

  • Fusion protein — This article is about chimeric fusion proteins. For proteins involved in membrane fusion, see membrane fusion protein. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes which originally coded for… …   Wikipedia

  • TauRx Therapeutics — Infobox Company name = TauRx Therapeutics type = Public genre = foundation = Singapore (2002) flagicon|Singapore founder = Professor Claude Wischik Dr K. M. Seng location city = location country = location = Singapore flagicon|Singapore locations …   Wikipedia

  • Bone morphogenetic protein — Bone Morphogenetic Proteins (BMPs) are a group of growth factors and cytokines known for their ability to induce the formation of bone and cartilage. TypesOriginally, seven such proteins were discovered. Of these, six (BMP2 through BMP7) belong… …   Wikipedia

  • Trubion — Trubion is a publicly held biopharmaceutical company that is focused on creating a pipeline of protein based therapeutic product candidates to treat autoimmune and inflammatory diseases and cancer. Trubion was established in 1999 in the State of …   Wikipedia

  • Chinese hamster ovary cell — Chinese hamster ovary (CHO) cells are a cell line derived from the ovary of the Chinese hamster. They are often used in biological and medical research and commercially in the production of therapeutic proteins.[1] They were introduced in the… …   Wikipedia

  • Antikörpermimetikum — Antikörpermimetika (engl. Antibody mimetics) sind Verbindungen, die wie Antikörper zur Bindung von Antigenen befähigt sind. Antikörpermimetika sind zumeist künstliche Peptide oder Proteine mit einer molaren Masse von etwa 3 bis 20 kDa, aber… …   Deutsch Wikipedia

  • Plasmapheresis — Pheresis redirects here. It is not to be confused with Phoresis. Plasmapheresis Intervention ICD 10 PCS 6A5 ICD 9 CM …   Wikipedia

  • DARPins — Strukturmodell eines DARPins basierend auf Röntgenstrukturanalysedaten (PDB 2QYJ) DARPins (kurz von engl. Designed Ankyrin Repeat Proteins) sind künstliche Proteine, die zur Erkennung und Bindung von Antigenen befähigt sind. Sie sind strukturell… …   Deutsch Wikipedia


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