Электронная книга: Brian Henderson «The Human Microbiota and Chronic Disease. Dysbiosis as a Cause of Human Pathology»

The Human Microbiota and Chronic Disease. Dysbiosis as a Cause of Human Pathology

Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity– periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play intheir induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Exploresthe relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.

Издательство: "John Wiley&Sons Limited"

ISBN: 9781118982884

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Brian Henderson

Infobox Person
name = Brian Henderson

image_size = 150
caption =
birth_date = birth date and age|1931|9|15
birth_place = Dunedin, Otago, New Zealand
death_date =
death_place =
education =
occupation = News presenter
spouse = Mardi Henderson
parents =
children =

Brian Weir Henderson (born 15 September 1931) is a New Zealand-born Australian television personality who hosted the Australian version of "Bandstand" from 1958 until 1972. Henderson also holds the record for the longest serving television news presenter, having read either the weekend or the weeknight news on Sydney station TCN-9 from January 1957 until his retirement in late November 2002. Henderson took part in the reunion with Channel Nine for the 50th birthday of Australian television in September 2006.

The tagline Henderson used to sign off at the end of every newscast was, interchangeably, "...and that's the way it is." [cite news|first=Jenny|last=Tabakoff|coauthors=Peatling, Stephanie|title=That's the way it is - Hendo to call it a night|url=http://www.smh.com.au/articles/2002/10/21/1034561445970.html|work=The Sydney Morning Herald|date=2002-10-22|accessdate=2007-05-28] or "the way it is"; the sign-off originally came from the American newsreader Walter Cronkite.

At the end of his final bulletin, Henderson's voice wavered as he told viewers it was time to watch the news, not present it:

"Not the way it was, as has been suggested, but for the last time, the way it is, this Friday the 29th of November, this is Brian Henderson - a sad Brian Henderson - saying not goodnight, this time, but goodbye." [ [http://www.powerhousemuseum.com/collection/database/index.php?irn=319756&search=brian+henderson&

"The Simpsons" Army Barracks have a Henderson Bandstand often mistakenly thought to be named after Brian Henderson and his show. The bandstand was actually named after Alex Henderson, a tenor horn player in the Army Band who rose to become the Director of Music in the Australian Army.


External links


NAME=Henderson, Brian
SHORT DESCRIPTION=Australian news presenter
DATE OF BIRTH=15 September 1931
PLACE OF BIRTH=Dunedin, Otago, New Zealand

Источник: Brian Henderson

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