Электронная книга: Michael Stumpf «Handbook of Statistical Systems Biology»

Handbook of Statistical Systems Biology

Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters. This book: Provides a comprehensive account of inference techniques in systems biology. Introduces classical and Bayesian statistical methods for complex systems. Explores networks and graphical modeling as well as a wide range of statistical models for dynamical systems. Discusses various applications for statistical systems biology, such as gene regulation and signal transduction. Features statistical data analysis on numerous technologies, including metabolic and transcriptomic technologies. Presents an in-depth presentation of reverse engineering approaches. Provides colour illustrations to explain key concepts. This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field.

Издательство: "John Wiley&Sons Limited"

ISBN: 9781119970613

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Michael Stumpf

Michael Stumpf (b. 1970) is scholar in the field of systems biology. He has made ample contributions to evolutionary genetics and population genetics.


Stumpf was born in Regensburg, Germany, and grew up in Straubing and Rothenburg ob der Tauber. He studied physics at the Universities of Tübingen, Sussex and Göttingen. Upon graduating with his diploma in physics, he went on to study as a graduate student at the University of Oxford, where he received his DPhil. in statistical physics in 1999. Whilst a graduate student he was a member of Balliol College. In 1999 Stumpf moved into biology and worked for three years at the Department of Zoology of the University of Oxford with Professor Robert May, Baron May of Oxford. During this time Stumpf held a fellowship at Linacre College. Since 2003 Stumpf works at the Centre for Bioinformatics at Imperial College, London. In 2007 Stumpf was appointed to the Chair of Theoretical Systems Biology at Imperial College, London[1], and in 2011 he was awarded the Rector's Medal for Excellence in Research Supervision[2].

Stumpf is married and is living in West London.


Stumpf’s research covers a variety of fields, including

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Источник: Michael Stumpf

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