Электронная книга: Mike Leach «Practical Flow Cytometry in Haematology. 100 Worked Examples»
The analysis of blood, bone marrow and tissue fluid specimens requires a multi-faceted approach with the integration of scientific data from a number of disciplines. No single discipline can operate in isolation or errors will occur. Flow cytometry is in a privileged position in that it can provide rapid analysis of specimens and it is often the first definitive investigation to produce results and help formulate a working diagnosis. This companion text to Practical Flow Cytometry in Haematology Diagnosis contains 100 worked examples drawn from real clinical cases presenting to the authors’ institution. Cases are illustrated with peripheral blood and bone marrow cytology, tissue pathology and cytogenetic and molecular data, which are integrated to generate, where appropriate, a diagnosis based on the WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. The spectrumof clinical cases includes adult and paediatric patients, and both neoplastic and reactive disorders. The cases appear in no particular order to challenge the reader to make their own diagnosis. The reader will review May−Grünwald−Giemsa (MGG)-stained films of peripheral blood and bone marrowaspirates presented alongside flow cytometric data and haematoxylin and eosin (H&E)-stained bone marrow and other tissue biopsy sections. Immunohistochemistry is used to further clarify the tissue lineage and cell differentiation. Cytogenetic studies using metaphase preparations are used to identify translocations and chromosome gains and losses whilst interphase fluorescence in situ hybridisation (FISH) studies and polymerase chain reaction (PCR) are used to identify gene fusions, gene rearrangements and deletions. Each case concludes with a discussion of the features that are important to making a diagnosis. The cases are also listed according to disease classification in the appendix so that the text can also be used as a reference. Practical Flow Cytometry in Haematology: 100 Worked Examples: Provides a practical, example-based resource for flow cytometry Demonstrates how flow cytometry results should be interpreted and applied to optimize patient care Includes both malignant and benign conditions Can be used in conjunction with Practical Flow Cytometry in Haematology Diagnosis, by the same author team (ISBN 9780470671207) Practical Flow Cytometry in Haematology: 100 Worked Examples is ideal for practicing haematologists and histopathologists with an interest in haematopathology, but particularly directed at trainee haematologists and scientists preparing for FRCPath and related examinations. Издательство: "John Wiley&Sons Limited"
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Книга | Описание | Год | Цена | Тип книги |
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Practical Flow Cytometry in Haematology Diagnosis | The accurate diagnosis of haematologic malignancies is a complex and challenging task. It routinely involves morphologic, molecular, cytogenetic and flow cytometric expertise. To determine what… — John Wiley&Sons Limited, электронная книга Подробнее... | электронная книга |
Mike Leach
College coach infobox
Name = Mike Leach
ImageWidth = 120px
Caption = Mike Leach
Title =
College = Texas Tech
Sport = Football
Conference = Big 12
CurrentRecord = 70–37
DateOfBirth = birth date and age|1961|3|9
Birthplace = Susanville, CA
DateOfDeath =
Deathplace =
OverallRecord = 70–37
Contract = $1,650,000 [http://www.redraiders.com/stories/081206/foo_081206014.shtml "The Lubbock Avalanche-Journal": Leach to become $2 million man] ]
BowlRecord = 5–3
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Championships =
Awards =
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Player =
Years =
Team =
Position =
Coach = Y
CoachYears = 1987
1988
1989
1989-1991
1992-1996
1997-1998
1999
2000-"present"
CoachTeams = Cal Poly (Assist.)
COD (Assist.)
Pori Bears
Iowa Wesleyan (OC)
Valdosta State (OC)
Kentucky (OC)
Oklahoma (OC)
Texas Tech
FootballHOF =
CollegeHOFID =
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Michael C. Leach (born birth date|1961|3|9 in
Personal
Although born to Frank and Sandra Leach in Susanville, California, Mike Leach claims
In 1986, Leach earned a law degree from
Leach is atypical among NCAA
Coaching career
Offensive scheme
Leach is known for building some very potent offenses, directing very prolific passing-oriented teams that have broken school and NCAA records at Valdosta State, Kentucky, Oklahoma, where he was offensive coordinator under
Texas Tech
The Leach-coached Red Raiders' best finishes came with their nine-win seasons in 2002, 2005, and 2007. In 2002, Tech swept its in-state conference rivals Baylor, Texas, and Texas A&M for the first time since 1997 and then defeated Clemson, 55–15, in the Tangerine Bowl. It was the Red Raiders' first postseason win since 1995 when they beat the Air Force Falcons in the Copper Bowl. In 2005, the Raiders opened their season with a 6–0 record, the best start since 1998, and defeated Oklahoma for the first time under Leach. Leach has built a strong passing offense at Tech. The Red Raiders have led the NCAA in passing yardage for four years in a row. At Tech, he inserted
Under Mike Leach, Texas Tech has been known for its high-scoring offense and come-from-behind victories. A 70–35 win over heavily favored TCU in 2004 began with TCU leading 21–0 with eight minutes remaining in the second quarter. Before Tech's scoring drives started, a TCU defensive back was caught mouthing into a TV camera, "They aren't going to score." Later in the season, Texas Tech beat Nebraska, 70–10, forcing the Cornhuskers to give up more points in a single game than they had before in their 114-year history. In 2005, the Red Raiders were losing to Kansas State, 13–10, late in the second quarter but won the game 59–20. Also in 2005, Tech had a halftime lead of 14–10 over Texas A&M. By the end of the game, they increased the margin to 56–17. It was the Aggies' worst loss to the Red Raiders in the 64-year-old series. [ [http://www.nytimes.com/2005/12/04/magazine/04coach.html?ei=5090&en=c9f46201dc95f91d&ex=1291352400&partner=rssuserland&emc=rss&pagewanted=all Coach Leach Goes Deep, Very Deep - New York Times] ] During the 2005 game against Texas A&M,
Leach also coached the biggest comeback in NCAA Division 1-A history in the
Mike Leach was chosen to coach the South team during the 2007 inaugural Inta Juice North-South All-Star Classic game.
At the end of the 2007 season, Leach was 65–37 with the Red Raiders, including 6–2 against the Texas A&M Aggies and 1–7 against the Texas Longhorns. [Mack Brown Football.com] With a 5–3 record, he is the all-time winningest coach in postseason play in Tech football history. Leach is one of only sixteen active college football coaches who have never had a losing season. Of those, he is among nine who have been a head coach for at least five seasons. [ [http://www.lubbockonline.com/stories/090307/col_090307027.shtml LubbockOnline.com - Texas Tech-SMU game facts 09/03/07] ]
In August 2006, Leach signed a five-year contract with Texas Tech that will pay him at least $10 million if he stays in place through 2010. Leach's guaranteed compensation will be $1.6 million in 2006, $1.65 million in 2007, $1.75 million in 2008, $1.85 million in 2009 and $2.15 million in 2010.
2007 Texas vs. Texas Tech controversy
During his post-game On 2008 season Leach, along with players Head coaching record CFB Yearly Record Subhead Notable accomplishments Texas Tech * 8 consecutive winning seasons ee also * References External links * [http://texastech.collegesports.com/sports/m-footbl/mtt/leach_mike00.html Player bio] Источник: Mike Leach
name=
conf=
startyear=2000
endyear=CFB Yearly Record Entry
year = 2000
name = Texas Tech
overall = 7–6
conference = 3–5
confstanding = 4th (South)
bowlname = galleryfurniture.com
bowlopponent = East Carolina
bowloutcome = 27-40 L
ranking = –
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year = 2001
name = Texas Tech
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confstanding = T-3rd (South)
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bowlname = Alamo
bowlopponent = Iowa
bowloutcome = 13-16 L
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name = Texas Tech
overall = 9–5
conference = 5–3
confstanding = T-2nd (South)
bowl = yes
bowlname = Tangerine
bowlopponent = Clemson
bowloutcome = 55-15 W
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year = 2003
name = Texas Tech
overall = 8–5
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confstanding = 4th (South)
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bowlopponent = Navy
bowloutcome = 38-14 W
ranking = –
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year = 2004
name = Texas Tech
overall = 8–4
conference = 5–3
confstanding = T-3rd (South)
bowl = yes
bowlname = Holiday
bowlopponent = California
bowloutcome = 45-31 W
ranking = 17
ranking2 = 18CFB Yearly Record Entry
year = 2005
name = Texas Tech
overall = 9–3
conference = 6–2
confstanding = T-2nd (South)
bowlname = Cotton
bowlopponent = Alabama
bowloutcome = 10-13 L
ranking = 19
ranking2 = 20CFB Yearly Record Entry
year = 2006
name = Texas Tech
overall = 8–5
conference = 4–4
confstanding = 4th (South)
bowlname = Insight
bowlopponent = Minnesota
bowloutcome = 44-41 W
ranking = –
ranking2 = –CFB Yearly Record Entry
year = 2007
name = Texas Tech
overall = 9–4
conference = 4–4
confstanding = T-3rd (South)
bowlname = Gator
bowlopponent = Virginia
bowloutcome = 31-28 W
ranking = 23
ranking2 = 22CFB Yearly Record Entry
year = 2008
name = Texas Tech
overall = 5–0
conference = 1–0
confstanding = T-1st (South)
bowlname =
bowlopponent =
bowloutcome =
ranking =
ranking2 = CFB Yearly Record Subtotal
name=Texas Tech
overall=70–37
confrecord=36–29CFB Yearly Record End
overall = 70–37
bcs = no
poll = two
* 8 consecutive bowl appearances
* 6 consecutive eight-win seasons
* 3 nine-win seasons
* 5 bowl wins (most by any individual coach in the history of the program)
* 3 seasons completed with team ranked in the Top 25
* 15–9 record against in-state conference rivals Baylor, Texas, and Texas A&M
* 42–10 record at
* Coached 1
* Coached 1
* Coached 3
* More than 150 NCAA, Big 12 and school records broken [ [http://sports.espn.go.com/ncf/columns/story?columnist=schlabach_mark&id=3385098 Eccentric Leach ready to lead Red Raiders to ultimate treasure] ]
*
* [http://www.texastech.com/ Texas Tech Red Raiders website]
* [http://www.nytimes.com/2005/12/04/magazine/04coach.html?ei=5090&en=c9f46201dc95f91d&ex=1291352400&adxnnl=1&partner=rssuserland&emc=rss&pagewanted=all&adxnnlx=1165295348-QhCHlsh+0Ca3wU8ESozzZA "New York Times" article: "Coach Leach Goes Deep, Very Deep"]
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