Электронная книга: Wood Michael W. «Targets and Emerging Therapies for Schizophrenia»

Targets and Emerging Therapies for Schizophrenia

New and emerging directions in pharmaceutical research to better treat schizophrenia Although the dopamine hypothesis has been the cornerstone of schizophrenia therapeutics, it is clear that dopamine-based approaches do not treat all aspects of the disease. Moreover, many schizophrenia patients fail to respond to current antipsychotics. Integrating chemistry, biology, and pharmacology, this book explores emerging directions in pharmaceutical research for drug targeting and discovery in order to find more effective treatments for schizophrenia, one of the most serious and widespread psychiatric diseases. Targets and Emerging Therapies for Schizophrenia presents the basics of schizophrenia, drug targets for the disease, and potential new drugs and therapeutics. It begins with a discussion of prevalence and etiology. Then, it describes therapies such as dopamine agonists and phosphodiesterase (PDE) inhibitors as well as growing research aimed at addressing untreated symptoms. Next, the authors discuss receptor modulators, inhibitors, and targeting strategies for drug discovery. Both the neurobiological and chemical aspects of all major pharmacological targets are examined. With contributions from an international team of pioneering pharmaceutical researchers, this book compiles the current knowledge in the field, setting the stage for new breakthroughs in the treatment of schizophrenia. Targets and Emerging Therapies for Schizophrenia: Provides a comprehensive resource for neuro-drug discovery and the development of molecular targets for schizophrenia treatment Draws from chemistry, biology, and pharmacology for more effective drug targeting and discovery Explores a wide range of receptors and molecular targets, including dopamine, PDEs, and neuropeptides With Targets and Emerging Therapies for Schizophrenia as their guide, drug discovery and development scientists have the information they need to advance their own research so that new, more effective treatments for schizophrenia will soon be a reality.

Издательство: "John Wiley&Sons Limited"

ISBN: 9781118309384

электронная книга

Купить за 15063.15 руб и скачать на Litres

Look at other dictionaries:

  • Health and Disease — ▪ 2009 Introduction Food and Drug Safety.       In 2008 the contamination of infant formula and related dairy products with melamine in China led to widespread health problems in children, including urinary problems and possible renal tube… …   Universalium

  • Life Sciences — ▪ 2009 Introduction Zoology       In 2008 several zoological studies provided new insights into how species life history traits (such as the timing of reproduction or the length of life of adult individuals) are derived in part as responses to… …   Universalium

  • Alzheimer's disease clinical research — As of August 2010 there were more than 800 clinical trials under way to understand and treat Alzheimer s disease. 149 of these studies were human phase three trials, the last step before U.S. Food and Drug Administration approval and marketing.… …   Wikipedia

  • MicroRNA — The stem loop secondary structure of a pre microRNA from Brassica oleracea. A microRNA (abbreviated miRNA) is a short ribonucleic acid (RNA) molecule found in eukaryotic cells. A microRNA molecule has very few nucleotides (an average of 22)… …   Wikipedia

  • Alzheimer's disease — Alzheimer redirects here. For other uses, see Alzheimer (disambiguation). Alzheimer s disease Classification and external resources …   Wikipedia

  • History of mental disorders — The history of mental disorder spans prehistoric times, ancient civilisations, the Middle Ages, the early modern period, the enlightenment and modern times.Prehistoric timesThere is limited evidence by which to judge the existence or nature of… …   Wikipedia

  • Huntington's disease — Classification and external resources A microscope image of …   Wikipedia

  • Список медицинских журналов — Содержание 1 А П 2 Р Я 3 A 4 B 5 C …   Википедия