Электронная книга: Daniele Martini De «Success Probability Estimation with Applications to Clinical Trials»
Provides an introduction to the various statistical techniques involved in medical research and drug development with a focus on estimating the success probability of an experiment Success Probability Estimation with Applications to Clinical Trials details the use of success probability estimation in both the planning and analyzing of clinical trials and in widely used statistical tests. Devoted to both statisticians and non-statisticians who are involved in clinical trials, Part I of the book presents new concepts related to success probability estimation and their usefulness in clinical trials, and each section begins with a non-technical explanation of the presented concepts. Part II delves deeper into the techniques for success probability estimation and features applications to both reproducibility probability estimation and conservative sample size estimation. Success Probability Estimation with Applications to Clinical Trials:• Addresses the theoretical and practical aspects of the topic and introduces new and promising techniques in the statistical and pharmaceutical industries Features practical solutions for problems that are often encountered in clinical trials Includes success probability estimation for widely used statistical tests, such as parametric and nonparametric models Focuses on experimental planning, specifically the sample size of clinical trials using phase II results and data for planning phase III trials Introduces statistical concepts related to success probability estimation and their usefulness in clinical trials Success Probability Estimation with Applications to Clinical Trials is an ideal reference for statisticians and biostatisticians in the pharmaceutical industry as well as researchers and practitioners in medical centers who are actively involved in health policy, clinical research, and the design and evaluation of clinical trials.
Издательство: "John Wiley&Sons Limited"
ISBN: 9781118548288 электронная книга Купить за 7492.55 руб и скачать на Litres
Купить за 7492.55 руб и скачать на Litres
Look at other dictionaries:
Randomized controlled trial — Flowchart of four phases (enrollment, intervention allocation, follow up, and data analysis) of a parallel randomized trial of two groups, modified from the CONSORT (Consolidated Standards of Reporting Trials) 2010 Statement … Wikipedia
Maximum likelihood — In statistics, maximum likelihood estimation (MLE) is a method of estimating the parameters of a statistical model. When applied to a data set and given a statistical model, maximum likelihood estimation provides estimates for the model s… … Wikipedia
Dynamic treatment regime — In medical research, a dynamic treatment regime (DTR) or adaptive treatment strategy is a set of rules for choosing effective treatments for individual patients. The treatment choices made for a particular patient are based on that individual s… … Wikipedia
Statistical hypothesis testing — This article is about frequentist hypothesis testing which is taught in introductory statistics. For Bayesian hypothesis testing, see Bayesian inference. A statistical hypothesis test is a method of making decisions using data, whether from a… … Wikipedia
Survey methodology — Sociology … Wikipedia
Experiment — Experimental redirects here. For the musical classification, see Experimental music. For other uses, see Experiment (disambiguation). Even very young children perform rudimentary experiments in order to learn about the world. An experiment is a… … Wikipedia
Regression toward the mean — In statistics, regression toward the mean (also known as regression to the mean) is the phenomenon that if a variable is extreme on its first measurement, it will tend to be closer to the average on a second measurement, and a fact that may… … Wikipedia
Opinion poll — An opinion poll, sometimes simply referred to as a poll is a survey of public opinion from a particular sample. Opinion polls are usually designed to represent the opinions of a population by conducting a series of questions and then… … Wikipedia
Prostate cancer — is a disease in which cancer develops in the prostate, a gland in the male reproductive system. It occurs when cells of the prostate mutate and begin to multiply out of control. These cells may spread (metastasize) from the prostate to other… … Wikipedia