Книга: Rajni Kant,Vivek Gupta and Preetika Sharma «Pharmaceutical Drug Polymorphism»

Pharmaceutical Drug Polymorphism

Производитель: "LAP Lambert Academic Publishing"

Polymorphism is not only interesting in the context of basic science, understanding the concepts of intermolecular interactions, but the industry dealing with materials as well as with pharmaceuticals, has also a huge stake in this area. For materials, control over the solid state is crucial for their physical properties, e. g. conductivity or strength, while for pharmaceutically active compounds, the form of the solid state structure can determine its activity potential. Polymorphs possess different properties, for instance the solubility or the mechanical resistance can differ dramatically from one polymorph to the other properties which can be crucial for their application. Hence, it is important to be able to control the formation of polymorphs and to understand their formation. Particularly for organic compounds, there seems to be a large number of polymorphs possible if for example many hydrogen bonds can be formed between the individual molecules. Thus, for many... ISBN:9783659230363

Издательство: "LAP Lambert Academic Publishing" (2013)

ISBN: 9783659230363

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См. также в других словарях:

  • Polymorphism (materials science) — Polymorphism in materials science is the ability of a solid material to exist in more than one form or crystal structure. Polymorphism can potentially be found in any crystalline material including polymers, minerals, and metals, and is related… …   Wikipedia

  • Drug metabolism — is the biochemical modification of pharmaceutical substances by living organisms, usually through specialized enzymatic systems. This is a form of xenobiotic metabolism. Drug metabolism often converts lipophilic chemical compounds into more… …   Wikipedia

  • Pharmaceutical formulation — Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. Contents 1 Stages and timeline 2 Oral formulations 2.1 Tablet form …   Wikipedia

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  • Aspirin — Asprin redirects here. For the author, see Robert Asprin. Aspirin …   Wikipedia

  • Cocrystal — The definition of a cocrystal has been debated in the crystallography field. The simplest definition of a cocrystal is a crystalline structure made up of two or more components in a definite stoichiometric ratio, where each component is defined… …   Wikipedia

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