Книга: Nir Hus «New Mechanism for Antibiotic Resistance Volume II»
|
Производитель: "LAP Lambert Academic Publishing" Volume II ynfA, of Escherichia coli (P76169 swissprot, g1787865 GenBank) is the newest member of the Small Multidrug Resistance (SMR) gene family. It was identified with the aid of bioinformatics tools that allowed us to follow evolutionary principles of sequence conservation, in which functional similarity is inferred from sequence similarity, but surprisingly biochemical data yielded an unexpected mode of action for YnfA. The SMR gene family represents a prokaryotic transport system that is restricted to the eubacterial kingdom and has been so far identified in 63 bacterial species in both gram-negative and -positive bacterial species. Members of this family are composed of 100-120 amino acid residues in length and span the membrane four times as ?-helices. A ynfA inframe deletion mutant was created from an isogenic wild type E. coli MG1655 that displayed no growth defect compared to its wild type isogenic pair. Thus the mutant displayed antibiotic resistance. ISBN:9783848483808 Издательство: "LAP Lambert Academic Publishing" (2012)
ISBN: 9783848483808 |
См. также в других словарях:
Antibiotic resistance — is a type of drug resistance where a microorganism is able to survive exposure to an antibiotic. While a spontaneous or induced genetic mutation in bacteria may confer resistance to antimicrobial drugs, genes that confer resistance can be… … Wikipedia
New Delhi metallo-beta-lactamase 1 — Klebsiella pneumoniae, the bacterium in which NDM 1 was first identified. New Delhi metallo beta lactamase 1 (NDM 1)[1] is an enzyme that makes bacteria resistant to a broad range of beta lactam … Wikipedia
History of biology — For the video game, see History of Biology (video game). The frontispiece to Erasmus Darwin s evolution themed poem The Temple of Nature shows a goddess pulling back the veil from nature (in the person of Artemis). Allegory and metaphor have… … Wikipedia
Evolutionary medicine — Charles Darwin’s daughter Anne, “the joy of the household” died aged 10 due to tuberculosis … Wikipedia
Transposon — Transposons are sequences of DNA that can move around to different positions within the genome of a single cell, a process called transposition. In the process, they can cause mutations and change the amount of DNA in the genome. Transposons were … Wikipedia
Agrobacterium — Taxobox color = lightgrey name = Agrobacterium image width = 200px regnum = Bacteria phylum = Proteobacteria classis = Alpha Proteobacteria ordo = Rhizobiales familia = Rhizobiaceae genus = Agrobacterium subdivision ranks = Species subdivision =… … Wikipedia
