Книга: Pratik Vora,Amruta Chaudhari and Gajanan Shinde «Nanostructured lipid carriers»
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Производитель: "LAP Lambert Academic Publishing" The objective was to formulate Silymarin into nanostructured lipid carriers (NLC) to enhance its sun screening efficacy and safety. NLC of Silymarin were prepared by the high pressure homogenization. The study design involves the investigation of the effect of two independent variables namely ratio of solid lipid and liquid lipid concentration (60:40, 70:30, 80:20 with respect to total lipid), and Tween 80 concentration (3%, 4% and 5%) on Surface morphology by SEM analysis, FTIR, DSC, particle size (PS), entrapment efficiency (%EE) and in-vitro drug release after 24 h. The prepared NLC were spherical in overall shape. Solid lipid and liquid ratio 70:30 and Tween 80 concentration 5% were found to significantly decrease the PS and increase the EE% with when used ethyl oleate concentration 30% (of total lipid concentration). Increasing Tween 80 concentration decreased significantly the particle size. But showing slightly effect on the %EE. Silymarin-loaded NLC dispersion was then... ISBN:9783659566325 Издательство: "LAP Lambert Academic Publishing" (2014)
ISBN: 9783659566325 |
См. также в других словарях:
nanotechnology — /nan euh tek nol euh jee, nay neuh /, n. any technology on the scale of nanometers. [1987] * * * Manipulation of atoms, molecules, and materials to form structures on the scale of nanometres (billionths of a metre). These nanostructures typically … Universalium
