Книга: Prasad M. G. S.,Shantipriya Reddy and Hrishikesh Asutkar «Host modulation in periodontics»
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Производитель: "LAP Lambert Academic Publishing" Periodontitis is a polymicrobial infectious disease of multifactorial origin. Plaque biofilm and associated host responses are involved in the pathogenesis of periodontitis. Organisms strongly implicated as etiologic agents include Gramnegative, anaerobic bacteria within the biofilm . The microbial challenge consisting of antigens,lipopolysaccharide (LPS), and other virulence factors stimulates host responses which result in disease. Protective aspects of the host response include recruitment of neutrophils, production of protective antibodies, and possibly the release of anti-inflammatory cytokines including transforming growth factor-? (TGF-?), interleukin-4, 10, 12 Perpetuation of the host response due to a persistent bacterial challenge disrupts homeostatic mechanisms and results in release of mediators including proinflammatory cytokines, proteases,and prostanoids which can promote extracellular matrix destruction in the gingiva and stimulate bone resorption. The determination that... ISBN:9783659139031 Издательство: "LAP Lambert Academic Publishing" (2012)
ISBN: 9783659139031 |
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Chronic periodontitis — is a common disease of the oral cavity consisting of chronic inflammation of the periodontal tissues that is caused by accumulation of profuse amounts of dental plaque. Chronic periodontitis Classification and external resources ICD 10 K05.3 ICD… … Wikipedia
