Книга: Sofiya Verma,Sandhya Chaurasia and Ashok Asati «Formulation and Characterization of Aceclofenac Microsphere»

Производитель: "LAP Lambert Academic Publishing"

The purpose of this research was to prepare and characterize Aceclofenac microsphere of guar gum polymer for the application of inflammation. Method: - The microsphere were prepared by using emulsification method using starch cross-linked agent and coating was done by solvent evaporation method with the pH sensitive eudragit S-100 polymers. Result:-The prepared microsphere were white, free flowing and spherical in shape. The drug-loaded microsphere showed entrapment efficiency and drug release was extended upto 6 to 8 h. The infrared spectra, differential scanning calorimetry thermographs spectra all showed the stable character of both the drugs in the drug-loaded microspheres and revealed the absence of drug-polymer interactions. Scanning electron microscopy study revealed that the microspheres were spherical and porous in nature. The stability study was conducted to conform the stability of prepared microsphere. In-vitro drug release study was performed in both simulated... ISBN:9783659202322

Издательство: "LAP Lambert Academic Publishing" (2012)

ISBN: 9783659202322