Книга: Apparao Potu,Burra Shashidher and Sandeep Pasunooti «Fenoprofen Calcium Compressed Coated Tablets for Colon Drug Delivery»

Fenoprofen Calcium Compressed Coated Tablets for Colon Drug Delivery

Производитель: "LAP Lambert Academic Publishing"

The aim of this study was to design and evaluate a colon targeting delivery for fenoprofen calcium with better benefits in treating the arthritis. Compression coated tablets were prepared by using guar gum as a coating material over core tablets. These systems would benefit for the high amount release of the drug in the distal intestinal or the colon, this may exhibit better fenoprofen calcium toward the arthritis by reduce the serious gastrointestinal (GI) adverse events including inflammation, bleeding, ulceration, and perforation of the stomach, small intestine or large intestine. Plan of work: 1) Formulation of fenoprofen calcium core tablets by direct compression. 2) Compression coating over the fenoprofen calcium core tablets using guar gum as a coating material. 3) Optimization of the coat thickness as the minimum that can provide protection against the gastric and intestinal environment. 4) Characterization of prepared powder mixer ? Angle of repose ? Bulk... ISBN:9783848497027

Издательство: "LAP Lambert Academic Publishing" (2012)

ISBN: 9783848497027

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