Книга: Mr.Maulik Patel,Dr. Sanjay Patel and Dr. Natvarlal Patel «Development of Self Microemulsifying Drug Delivery System»
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Производитель: "LAP Lambert Academic Publishing" Nearly 40% of new drug candidates exhibit low solubility in water, which leads to poor oral bioavailability, high intra- and inter-subject variability and lack of dose proportionality. Modification of the physicochemical properties, such as salt formation and particle size reduction of the compound may be one approach to improve the dissolution rate of the drug. However, these methods have their own limitations. In recent years, much attention has focused on lipid based formulations to improve the oral bioavailability of poorly water soluble drugs. In fact, the most popular approach is the incorporation of the drug compound into inert lipid vehicles such as oils, surfactant dispersions, self-emulsifying formulations, emulsions and liposomes with particular emphasis on self-microemulsifying drug delivery systems (SMEDDS). ISBN:9783844331820 Издательство: "LAP Lambert Academic Publishing" (2011)
ISBN: 9783844331820 |
См. также в других словарях:
Drug delivery — For the scientific journal Drug Delivery , see Drug Delivery (journal). Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals.[1][2] Drug delivery technologies… … Wikipedia
