Книга: Kunal Kapadia,Jigna Shah and Parloop Bhatt «Altered Thyroid State and Development of Insulin Resistance»
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Производитель: "LAP Lambert Academic Publishing" The prevalence of thyroid disease in patients with diabetes is significantly higher than that in the general population. This indicates a possible interplay between thyroid status and insulin sensitivity. Complex interplay between thyroid function and insulin resistance (IR) has been implicated in diabetic dyslipidemia. Homeostatic model assessment (HOMA) of ?-cell function and IR is a method for assessing ?-cell function and IR from basal glucose and insulin or C-peptide concentrations. The use of HOMA to estimate insulin sensitivity and ?-cell function helps to compare ?-cell function and insulin sensitivity In the light of the existing reports we decided to 1) evaluate the correlation between altered thyroid state and development of IR clinically; 2) to assess ? cell function and IR by HOMA-IR. Our study concluded that thyroid disorder, including both hypo- and hyper, have been associated with IR due to various mechanism like altered insulin secretion and lipid levels. Thus even... ISBN:9783659162794 Издательство: "LAP Lambert Academic Publishing" (2012)
ISBN: 9783659162794 |
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