Книга: Priya Mehrishi,Shinu Pottathil and Varsha A. Singh «Isolation of Mycobacterium tuberculosis»

Isolation of Mycobacterium tuberculosis

Производитель: "LAP Lambert Academic Publishing"

The study was designed to compare the ef?cacy of cetylpyridinium chloride (CPC) and sodium chloride (NaCl) decontamination method with N-acetyl L-Cystine (NALC) and sodium hydroxide (NaOH) decontamination (the reference method) method for the recovery of Mycobacterium tuberculosis (MTB) from clinically suspected cases of pulmonary tuberculosis. To evaluate CPC-NaCl and NALC-NaOH decontamination methods, sputum specimens (n = 100) were studied (culturing on Lowenstein-Jensen medium), and the performances were compared. The CPC-NaCl decontamination method demonstrated a sensitivity, speci?city, negative predictive value, and positive predictive value of 100%, 87. 63%, 20%, and 100%, respectively, when compared to NALC-NaOH decontamination method. In summary, CPC-NaCl decontamination method effectively detected signi?cantly higher number of MTB cases (n = 15) than NALC-NaOH decontamination method (n = 3) particularly in sputum with scanty bacilli and smear-negative cases, indicating the... ISBN:9783659529702

Издательство: "LAP Lambert Academic Publishing" (2014)

ISBN: 9783659529702

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