Книга: Sonja Pritchett «Investigating X-Chromosome Inactivation»
|
Производитель: "LAP Lambert Academic Publishing" Females have two alleles for each gene on the X- chromosome, whereas males have only one. This inequality is balanced by X-chromosome inactivation (XCI). This process transcriptionally silences one X- chromosome in every female cell. The choice of which X-chromosome should be turned-o? is considered to be random. Studies on mice have revealed that a locus on the X-chromosome, the X controlling element (Xce), signi?cantly in?uences the choice of which X- chromosome is inactivated. Renault et al. (2007) studied a family of which many of the females exhibit symptoms of the X-linked recessive disease, Haemophilia A. The XCI ratios of the women in this family were signi?cantly di?erent from what would be expected if the XCI process was random. This studies result is consistent with the human XCE hypothesis. Random and genetic models of XCI ratios are investigated here in theory and are compared to a sample of XCI ratios. Using goodness-of- fit testing, it is determined... ISBN:9783843390064 Издательство: "LAP Lambert Academic Publishing" (2011)
ISBN: 9783843390064 |
См. также в других словарях:
Life Sciences — ▪ 2009 Introduction Zoology In 2008 several zoological studies provided new insights into how species life history traits (such as the timing of reproduction or the length of life of adult individuals) are derived in part as responses to… … Universalium
Ernest Beutler — (September 30, 1928 – October 5, 2008), a hematologist and biomedical scientist, was born in Berlin, Germany, the son of Jewish parents (Alfred and Kaethe, née Italiener). Both of his parents were also physicians, and his mother, a pediatrician,… … Wikipedia
Queen's Medal — Die Royal Medal, auch The Queen s Medal genannt, ist eine von der Royal Society verliehene Auszeichnung für Wissenschaftler, die innerhalb des Commonwealth of Nations besonders wichtige Beiträge zur Weiterentwicklung der Wissenschaften geleistet… … Deutsch Wikipedia
Royal Medal — Die Royal Medal, auch The Queen s Medal genannt, ist eine von der Royal Society verliehene Auszeichnung für Wissenschaftler, die innerhalb des Commonwealth of Nations besonders wichtige Beiträge zur Weiterentwicklung der Wissenschaften geleistet… … Deutsch Wikipedia
Human genetics — describes the study of inheritance as it occurs in human beings. Human genetics encompasses a variety of overlapping fields including: classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics, population genetics,… … Wikipedia
Anthropology and Archaeology — ▪ 2009 Introduction Anthropology Among the key developments in 2008 in the field of physical anthropology was the discovery by a large interdisciplinary team of Spanish and American scientists in northern Spain of a partial mandible (lower… … Universalium
