Книга: Jitendra Singh Yadav,Arti Gupta and Rumit Shah «Formulation and Evaluation of Buccal Drug Delivery»
|
Производитель: "LAP Lambert Academic Publishing" For systemic delivery, the oral route has been the preferred route of administration for many systemic actively drugs. When administered by the oral route, however, many therapeutic agents have been reportedly subjected to extensive presystemic elimination by gastrointestinal degradation and/or hepatic metabolism. Results of low systemic bioavailability, short duration of therapeutic activity, and/or formation of toxic and inactive metabolite. The unique environment of the oral cavity offers its potential as a site for drug delivery. Because of rich blood supply and direct access to systemic circulation, the oral mucosal route is suitable for drugs, which are susceptible to acid hydrolysis in the stomach or which are extensively metabolized in the liver. ISBN:9783659114335 Издательство: "LAP Lambert Academic Publishing" (2012)
ISBN: 9783659114335 |
См. также в других словарях:
Buccaltablette — Eine Buccaltablette (von lateinisch bucca: Wange) ist eine tablettenähnliche Arzneiform, die zur Freisetzung des Arzneistoffes in der Mundhöhle verbleibt. Prinzipiell werden Buccaltabletten für zwei verschiedene Anwendungszwecke hergestellt, je… … Deutsch Wikipedia
Topical — This article is about topical medications. For other uses, see Topic (disambiguation). In medicine, a topical medication is applied to body surfaces such as the skin or mucous membranes such as the vagina, anus, throat, eyes and ears. Many… … Wikipedia
Hormone replacement therapy (female-to-male) — Hormone replacement therapy (HRT) for transgender and transsexual people replaces the hormones naturally occurring in their bodies with those of the other sex. However, not all cases of hormone replacement therapy are used by transgendered people … Wikipedia
Duragesic — and Durogesic ( /ˌdɜrə … Wikipedia
