Книга: Karthikeyan Subburayan «Ferulic acid modulates radiation effects in cancer cells in vitro»

Ferulic acid modulates radiation effects in cancer cells in vitro

Производитель: "LAP Lambert Academic Publishing"

Cervical cancer is one of the deadliest cancers in women with a death total of 230, 000 worldwide each year, nearly 80% in developing countries. Radiotherapy (RT) is a major treatment modality for advanced cervical cancer but the local relapse rate is 30 44% in patients treated with RT alone and 19 25% in patients treated with concurrent chemoradiotherapy. We have investigated the radiosensitizing effect of ferulic acid (FA), a naturally occurring phenolic phytochemical, against gamma-radiation induced cell death in human cervical (HeLa, ME-180 and SiHa) cancer cells. Percentage of growth inhibition, intracellular ROS levels, mitochondria membrane potential, oxidative DNA damage and apoptotic morphology changes were measured. On the whole, the findings will hopefully provide this radiosensitizing effect of ferulic acid and/or gamma radiation associated to reduces the patient s expenses and risks of toxicity, as well as over the currently available radiotherapy treatments for... ISBN:9783659416019

Издательство: "LAP Lambert Academic Publishing" (2013)

ISBN: 9783659416019

См. также в других словарях:

  • Caffeic acid — Chembox new Name = Caffeic acid ImageFile = Caffeic acid.svg ImageName = Caffeic acid ImageFile1 = CaffeicAcid3d.png ImageName1 = Caffeic acid IUPACName = 3 (3,4 Dihydroxyphenyl 3,4 Dihydroxy cinnamic acid trans Caffeate 3,4 Dihydroxy trans… …   Wikipedia

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